Via BBC:

A molecule designed to find, latch onto, then treat hardened arteries could offer a new way to tackle heart disease, say its inventors.

Nanoburrs, developed at the Massachusetts Institute of Technology (MIT), target only damaged cells in blood vessel walls.

Once attached, they can release drugs in precisely the right place.

But the British Heart Foundation warned the technology was some years from being used in patients.

The hardening of the arteries which supply the heart, or atherosclerosis, can eventually lead to blockages which can cause heart attacks.

The study in the Proceedings of the National Academy of Sciences journal says specialists normally use tiny balloons to force open the vessels, then place a tube called a stent inside to keep it open.

Often the process triggers a rapid re-growth of tissue around the stent which can lead to the artery blocking again, and a recent advance has been a stent which releases drugs for a number of days after insertion to keep this process under control.

The MIT approach offers another way to get these drugs to exactly the right place.

Its nanoburrs are coated with proteins which can only stick to a structure in the blood vessel wall called the "basement membrane".

This is only exposed when the wall is damaged, so only damaged sections of blood vessel are targeted.

Once in place, a reaction takes place to release the drug over a prolonged period - up to 12 days so far.

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Via NewScientist:

You can't get blood from a stone, but it seems you can make imitation red blood cells from polymers.
Just like real blood cells the pretenders can squeeze through spaces much smaller than their own diameter and absorb and release substances to order, including oxygen.
They could be used to disperse drugs, or the contrast agents used in medical imaging, throughout the body with fewer side effects than direct injection.
The fake cells could also be given to people who have lost blood instead of a blood transfusion.

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Artikel over Fereidoun M. Esfandiary, een belangrijke transhumanist.

Via CBS News: Morley Safer Reports On The Amazing Science Of Regenerative Medicine Growing Body Parts.
(CBS) It sounds like science fiction, but the fact is biotech companies and the government are pouring hundreds of millions of dollars into research they hope will one day make it possible for us to grow new body parts.

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Originele post via: R&D Daily Thursday, December 10, 2009

Invetech, an innovator in new product development and custom automation for the biomedical, industrial and consumer markets, today announced that it has delivered the world's first production model 3D bio-printer to Organovo, developers of the proprietary NovoGen bioprinting technology. Organovo will supply the units to research institutions investigating human tissue repair and organ replacement.

Dr. Fred Davis, president of Invetech, which has offices in San Diego and Melbourne, said, “Building human organs cell-by-cell was considered science fiction not that long ago. Through this clever combination of technology and science we have helped Organovo develop an instrument that will improve people’s lives, making the regenerative medicine that Organovo provides accessible to people around the world.”

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”Scientists and engineers can use the 3-D bio printers to enable placing cells of almost any type into a desired pattern in 3-D,” said Murphy. “Researchers can place liver cells on a preformed scaffold, support kidney cells with a co-printed scaffold, or form adjacent layers of epithelial and stromal soft tissue that grow into a mature tooth. Ultimately the idea would be for surgeons to have tissue on demand for various uses, and the best way to do that is get a number of bio-printers into the hands of researchers and give them the ability to make three dimensional tissues on demand.”

(...)

Invetech plan to ship a number of 3D bio-printers to Organovo during 2010 and 2011 as a part of the instrument development program. Organovo will be placing the printers globally with researchers in centers of excellence for medical research.

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